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The purpose of this study is to define the effect of 4 week monotherapy with with an oral antagonistof cysteinyl leukotriene receptors (CysLT1) montelukast on the secretion of regulatory cytokines, IL-10 and TGF-beta, bronchial hyperresponsiveness and clinical parameters in atopic asthma children. The methods used will enable us to investigate which cell subset is a target for a possible effect of montelukast on the regulation of these immunoregulatory cytokines.
Short description of the task performed by Croatian partner