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An european network for myelofibrosis consensus on definition of disease improvement and biological impact of new therapies
Project status:
From: 2002-11-01
To: 2005-10-31
(Completed)
Contract number:
Action line:
Type (Programme):
FP5
Instrument:
Project cost:
878.344,00 EUR
Project funding:
855.844,00 EUR
Project coordinator
Organisation Name:
IRCCS POLICLINICO SAN MATTEO - ISTITUTO DI RICOVERO E CURA A CARATTERE SCIENTIFICO
Organisation adress:
Organisation country:
Italija
Contact person name:
Giovanni AZZARETTI
Contact person email:
Croatian partner
Organisation name:
Medicinski fakultet
Organisation address:
UNIVERSITY HOSPITAL MERKUR ZAGREB, I. Zajca 19
Contact person name:
BACIC, Stjepan
Contact person tel:
Contact person fax:
Contact person e-mail:
Partners
Organisation name
Country
Short description of project
This project intends to provide a mechanism whereby new and promising approaches to the management of Myelofibrosis with Myeloid Metplasia (MMM)can be tested in a systematic and scientific manner. This objective will be the effort of a research network which first goal will be to offer to the scientific community a definition of improvement for MMM that will facilitate the standardization, conduct, interpretation and efficiency of clinical trials and might also be useful to physicians to decide how severe is the disease and if responded adequately to therapy in routine clinical practice. Selection of outcome variables through international surveys, and a combination of statistical and consensus techniques will be the methodologies used. Moreover, as a prototype of future studies, the role of cellular tyrosine kinase pathway in the myeloproliferation and the biological outcomes of a tyrosine kinase inhibitor, STI 571, will be evaluated.
Short description of the task performed by Croatian partner